PDSNGL™S is a premium-grade, single-source Polydeoxyribonucleotide (PDRN) ingredient obtained exclusively from highly purified salmonid sperm DNA, purified to contain DNA fragments 50–1500 kDa. Widely used in injection therapy for hair growth and supportive for skin and wound regeneration.
Cat No.: EG-RM-PDS-1-2ml
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PRODUCT INFORMATION |
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I. TECHNICAL SPECIFICATIONS |
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Structural / Composition Data |
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Structure / Formula |
Polydeoxyribonucleotide; linear polymer of 2'-deoxyribonucleotides (50-1500 base pairs) |
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Molecular Weight |
~50 - 1,500 kDa (Mixture of fragments) |
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Appearance |
Liquid |
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Purity |
≥ 95% |
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Solubility |
Soluble in aqueous buffers (e.g., saline, sterile water) |
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Form(s) Available |
Sterile solution |
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Stability & Shelf Life |
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Storage |
12 months at 2–8 °C, >24 months at –20 °C |
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Post-Reconstitution |
6-12 months at 2–8 °C |
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Stability Notes |
Protect from light |
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Quality & Compliance |
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QC Tests |
Pending validation |
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Intended Use |
As instructions |
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Documentation |
Available on request |
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II. PREPARATION / RECONSTITUTION |
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General Guidance |
Reconstitute with 1.0 mL sterile water to obtain 100 mg/mL. |
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Recommendations |
Use within 8–12 hours refrigerated. |
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III. MECHANISM & BIOLOGICAL FUNCTION |
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Mechanism of Action |
Binds to and activates the Adenosine A2A Receptor (A2AR). Acts as a "building block" and signaling molecule, promoting tissue repair and modulating inflammation. Promotes angiogenesis via VEGF upregulation. |
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Biological Claims |
• Tissue Regeneration & Wound Healing • Powerful Anti-Inflammatory Action • Stimulation of Angiogenesis (new blood vessel formation) • Collagen Synthesis & Fibroblast Proliferation |
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IV. APPLICATIONS |
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Intended Uses |
Targeted drug delivery systems |
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V. PACKAGING & PRESENTATION |
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Sizes |
1000 PPM / vials |
5000 PPM / vials |
10000 PPM / vials |
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Purified DNA fragments
Effective cellular stimulation
Clinically used
Supports hair growth
Promotes skin healing
High-purity extraction
Cream
Injectables
Hydrogel matrices
PDSNGL™-S delivers highly purified, low-molecular-weight polydeoxyribonucleotides that are rapidly metabolized into nucleotides and nucleosides by local enzymes. These building blocks support DNA , accelerate cell metabolism, and activate purinergic (A₂A) receptors, which in turn stimulate fibroblast proliferation, collagen and extracellular-matrix production, angiogenesis, and anti-inflammatory signaling. Together these effects create an optimal microenvironment for faster wound closure, improved skin regeneration, and revitalization of hair follicles through enhanced vascular supply and prolonged anagen (growth) phase activity.
The underlying active—single-source salmon-derived PDRN—has been investigated in multiple peer-reviewed preclinical and clinical studies demonstrating accelerated wound healing, enhanced angiogenesis, and increased hair density when applied topically or via injection.
PDSNGL™-S uses the same active principle but with tighter fragment-size control and enhanced purification to deliver consistent, reproducible performance.
Yes. PDSNGL™-S is manufactured under GMP-aligned and ISO-certified quality systems with strict controls on raw material sourcing, endotoxin levels, and microbial contamination. Each production batch is tested for identity, purity, and safety, and a detailed Certificate of Analysis (CoA) is supplied with every shipment to verify compliance with these standards.